“Prolozone is a technique that marries concepts from neural therapy, Prolotherapy, and ozone therapy.
It involves injecting various combinations of procaine, anti-inflammatory medications/homeopathics, vitamins,
minerals, proliferatives, and a mixture of ozone/oxygen gas into degenerated or injured joints, and into areas of pain. The result of this combination is nothing short of remarkable in that damaged tissues can be regenerated, and otherwise untreatable pain can be permanently cured.
What a Prolozone Patient Can Expect
“The first thing that most patients notice after a Prolozone treatment is an almost immediate 50-80% decrease in pain. This is in part due to the effect of the procaine. But ozone itself has a significant ability to directly relieve pain.
A 2009 article published in the European Journal of Pharmacology demonstrated that a single subcutaneous injection of ozone prevents allodynia and decreases the over-expression of pro-inflammatory caspases in the orbito-frontal cortex of neuropathic mice, immediately eliminating any signs of pain.
Lamberto Re, a medical doctor and soccer team physician in Verona, Italy routinely injects the acutely injured areas of his players with ozone alone. He does not use procaine. And he reports a marked decrease in pain as well as an improved rate of healing.
Next, chronic areas of degeneration such as in osteoarthritic knees, hips, and ankles will regenerate.
Although more research is needed to fully document this effect, some physicians have already taken pre and post treatment x-rays that have shown an increase in cartilage thickness in knees treated with Prolozone.
And fortunately, other than a rarely occurring and temporary increase in pain in the area injected, no significant side effects from Prolozone have ever been demonstrated. Other than the possibility of an allergy to one of the liquid components, there are no contraindications to its use.”
Conditions That Respond
The primary criterion for selecting a patient for Prolozone is pain. If it hurts, Prolozone should be tried. I have had cases in which the chief complaint was instability, and the patient had no complaints of pain. A classic example would be a recurring dislocating shoulder. Whereas Prolozone has worked well in many of these cases, my experience is that it should be combined with classical Prolotherapy for best results.
The following is a list of conditions that have been found to be very responsive to Prolozone: chronic neck and back pain from any cause, rotator cuff injuries, degenerative and arthritic hips, knees, and ankles, degenerated discs, plantar fasciitis, carpal tunnel syndrome, TMJ, sciatica, heel spurs, neuromas, tennis elbow, sinus infections, pelvic disorders, dental infections, post-op pain, non-union fractures, painful scars, and sports injuries—basically anything that hurts. ”
Conditions responsive to Prolozone
• Carpal tunnel syndrome
• Chronic back pain
• Chronic neck pain
• Degenerated discs
• Degenerative & arthritic ankles
• Degenerative & arthritic hips
• Degenerative & arthritic knees
• Dental infections
• Heel spurs
• Non-union fractures
• Painful scars
• Pelvic disorders
• Plantar fasciitis
• Post-op pain
• Rotator cuff injuries
• Sinus infections
• Sports injuries
• Tennis elbow
*above info from Dr. F. Shallenberger – article published in the Journal of Prolotherapy 2011.
A small amount of an ozone and oxygen mixture (up to 10 ml) are injected into the patient like a normal injection would be. This method is commonly used to treat allergies and inflammatory diseases, and is sometimes utilized as an adjunct to traditional cancer therapies in Europe.
Infiltration with Ozone (1 to 20 ml volume depending on the size of the joint) Infection blocking and immune activating, especially on shoulder and knee joint diseases.
|Intraarticular injection (mainly knee and shoulder)||Rheumatoid arthritis,
traumatic knee disorders
activation of SOD as radical scavanger,
activation of immunocompetent and cartilage cells,
release of TGF-ß